Using a combination of protein engineering and microscopy techniques, investigating how in endothelial cells Src kinase activates Rho GTPases and subsequently regulate adherens junctions and the barrier.
Utilizes engineered allosterically regulatable proteins in order to interrogate the role of Src signaling through its substrates to elicit degradation of the extracellular matrix and endothelial cell migration contributing to angiogenesis.
Cell Receptors & Signaling
Cell Migration & Interactions
Anne-Marie Ray, PhD
9/14 - 9/16
Maulik Patel, PhD
3/13 - 9/14
Current Position: UCSD, Pfizer Research Postodctoral Fellowship, Clinical Pharmacology-Oncology