Dai Z, Li M, Wharton J, Zhu MM, Zhao YY. PHD2 deficiency in endothelial cells and hematopoietic cells induces obliterative vascular remodeling and severe pulmonary arterial hypertension in mice and humans through HIF-2alpha.Circulation. 133:2447-2458, 2016.
Huang X, Dai Z, Cai L, Sun K, Cho J, Albertine KH, Malik AB, Schraufnagel DE, Zhao YY. Endothelial p110gammaPI3K mediates endothelial regeneration and vascular repair following inflammatory vascular injury. Circulation. 133:1093-1103, 2016.
Tran K, Zhang X, Predescu D, Huang X, Machado RF, Gothert JR, Malik AB, Valyi-Nagy T, Zhao YY. Endothelial Beta-catenin signaling is required for maintaining adult blood-brain barreri integrity and central nervous system homeostasis.Circulation. 133:177-186, 2016.
Zhao YD, Huang XJ, Yi F, Dai Z, Qian Z, Tiruppathi C, Tran K, Zhao YY. Endothelial FoxM1 mediates bone marrow progenitor cell-induced vascular repair and resolution of inflammation following inflammatory lung injury. Stem Cells.32:1855-1864, 2014.
Mirza MK, Sun Y, Zhao YD, SK Potula HH, Frey RS, Vogel SM, Malik AB, Zhao YY. FoxM1 regulates re-annealing of endothelial adherens junctions through transcriptional control of b-catenin. J Exp Med. 207:1675-1685, 2010.
Zhao YY*, Zhao YD, Mirza MK, Huang JH, SK Potula HH, Vogel SM, Brovkovych V, Yuan JXJ, Wharton J, Malik AB. Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through protein kinase G nitration. J Clin Invest.119:2009-2018, 2009. (*Correspondent).
Zhao YY*, Gao XP, Zhao YD, Mirza MK, Frey RS, Kalinichenko VV, Wang IC, Costa RH, Malik AB. Endothelial cell-restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injury. J Clin Invest. 116:2333-2343, 2006. (*, Correspondent).
Zhao YY, Liu Y, Stan RV, Fan L, Gu Y, Dalton N, Chu PH, Peterson K, Ross J Jr, Chien KR. Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice. Proc Natl Acad Sci USA. 99:11375-11380, 2002.
Crone S*, Zhao YY*, Fan L, Gu YS, Minamisawa S, Peterson K, Chen J, Kahn R, Condorelli G, Ross J Jr, Chien KR, and Lee KF. ErbB2 myocyte survival pathways are essential in the preventio of dilated cardiomyopathy. Nat Med. 8:459-465. (*, contributed equally).