Lab Contact Info

LAB:  909 S Wolcott

        4040 COMRB

PH #:  (312) 355-0251

FAX:  (312) 996-1225

Malik Lab

Current Lab Members

Kurt Bachmaier, MD, PhD

Research Assistant Professor

kbachmai@uic.edu

Inflammation protects the body from infection and simultaneously causes damage to multiple organs thereby endangering the host. We try to learn more about the mechanisms that control the organ damaging inflammatory responses.

Anke Di, MD, PhD

Research Assistant Professor

ankedi@uic.edu

Determine the role of regulated exocytosis in immune cells and determine the role of ion channel expression and its function.

Xiaopei Gao, MD

Research Assistant Professor

xgao@uic.edu

Publications​​​​​​​

Determine the regulation of endothelial activation in systemic sepsis and localized pneumonia by targeting the pathophysiological processes that cause potential lethal lung edema following system (i.p.) bacterial infection.

Glenn Marsboom, PhD

Research Assistant Professor

gmarsboo@uic.edu

Publications​​​​​​​

Address the role of fibroblasts in the genesis of pulmonary hypertension. Experiments will take advantage of physiological, cell and molecular biology approaches as well as novel mouse genetic models.

Zhigang Hong, PhD

Research Assistant Professor

zgh@uic.edu

Publications​​​​​​​

Alessandro Parodi, PhD

Research Assistant Professor

aparodi@uic.edu

Studying pulmonary drug delivery and regenerative lung medicine.

Shiqin Xiong, PhD

Research Assistant Professor

sxiong03@uic.edu

Publications​​​​​​​

The hallmarks of acute lung injury (ALI) include severe inflammation, lung vascular injury, and pulmonary edema. We posit that enabling endothelial regeneration post lung vascular injury protects against edema formation and improves survival. The mechanism underlying endothelial regeneration and lung injury repair by employing scRNA-SEQ and advanced technologies.

Kaori Yamada, PhD

Research Assistant Professor

horiguch@uic.edu

Publications​​​​​​​

Studying the regulation of cell polarity; PIP3 lipid trafficking by GAKIN/KIF13B, and its role in polarity determination; microtubule-stimulated ATPase activity of GAKIN, and its regulation by human DIG tumor suppressor.

Li Zou, MD, PhD

Instructor

liz001@uic.edu


Focus on stem cells, and the development of novel methods to differentiate PSCs into specific cell lineages.

Shejuan An, PhD

Postdoctoral Research Associate

ansjuan@uic.edu

Publications​​​​​​​

Previous focus on tumor biology and translational research, especially in lung cancer. Current research focus on lung injury, macrophage and endothelial cell biology.

Hojin Kang, PhD

Postdoctoral Research Associate

hobbang4@uic.edu

The role of fluid shear stress in angiogenesis and enodothelium permeability in three deminesional (3D) model.

Jeffrey Klomp, PhD

Postdoctoral Research Associate

klompja@uic.edu

Studying evolution of core gene expression modules, in particular molecular evolution of the vertebrate endothelial cell and transcriptional modeling of the endothelial cell hypoxic response.

Andrew Stuart, PhD

Postdoctoral Research Associate

acstuart@uic.edu

Investigating the interactions of protein based nanoparticles with polymorphonuclear leukocytes and endothelial cells, with the goal of improved drug targeting and delivery.

Guilan Liu

Research Specialist

guilan@uic.edu

James Hyun

Predoctoral Student

jhyun9@uic.edu


Ankit Jambusaria

Predoctoral Student, BioE

ajambu2@uic.edu

Developing novel bioinformatics approaches to study the heterogeneity of vascular endothelial cells and identify tissue-specific "signatures" of endothelial cells in response to inflammatoryor metabolic stress.

Vanessa Juettner

Predoctoral Student

vvullm2@uic.edu

Focus on the biomechanistic relationships of VE-PTP (vascular endothelial protein tyrosine phosphatase) and the VE-cadherin in lung endothelial cells.

Joshua Jones

MD, PhD Student

jjones56@uic.edu

Characterizing the role of endothelial specific Plasmalemmal Vesicle Associated Protein (PV1) in receptor mediated albumin transport in lung microvascular endothelial cells.

Mohammad (Aziz) Khan

Predoctoral Student, BioE

mkhan78@uic.edu

PECAM1 mediated signaling to promote cell polarization.

Menglin Liu

Predoctoral Student

mliu69@uic.edu

Working on how hypoxia influences lung vascular repair responses; comparing the mice lung permeability after different time points of LPS-induced injury.

Megan Rexius-Hall

Predoctoral Student, BioE

rexius1@uic.edu

Designs microfluidic devices to generate oxygen landscapes and evaluate the real-time intercellular communication between cells exposed to varying oxygen levels.

Research Interests

Vascular Biology

Lung Biology & Pathophysiology

Inflammation Signaling Mechanisms

Cell Receptors & Signaling

Stem Cell Biology & Regenerative Medicine

Past Trainees

PREDOCTORAL STUDENTS​​​​​​​