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LUNG T32

Participating Mentors

Program Eligibility

& Nominations

Dr. Asrar B Malik


Program Director

Department of Pharmacology

Center for Lung and Vascular Biology

University of Illinois College of Medicine

835 S Wolcott Ave E403

Chicago, IL 60612


                    Tel:        (312) 996-7635

                    Fax:       (312) 996-1225

                    E-mail:  abmalik@uic.edu

Current list of mentors who participate in the University of Illinois College of Medicine Lung Biology and Pathobiology Training Program.

Name

Primary (& Secondary) Appointments

Role in Program

Research Interests

Asrar B. Malik, PhD

Schweppe Family
Distinguished
Professor & Head

Pharmacology
Center for Lung & Vascular Biology

Principal
Investigator

Regulation of barrier properties of lung endothelial cells; cellular and molecular basis of lung endothelial activation and injury; neutrophil/endothelial interactions; lung progenitor cell

Biochemistry & Molecular Genetics (Medicine, Division of Pulmonary, Critical Care, Sleep and Allergy)

(Medicine, Division of Hematology/ Oncology)

Mentor

Eosinophil effector functions in asthma, tissue remodeling and fibrosis; biochemistry, cell and structural

biology of eosinophil protein

mediators of inflammation

Marcelo G. Bonini, PhD

Associate Professor

Medicine, Division of Cardiology
(Pharmacology)
(Pathology)

Mentor

Oxidative signaling and suppression of cytokine signaling enzymes pathogenic remodeling of the lung vasculature

Jaehyung "Gus" Cho, PhD

Associate Professor

Pharmacology
(Anesthesiology)

Mentor

Molecular mechanisms of platelet and role in thrombus formation and vascular inflammation

Wonhwa Cho, PhD
Distinguished Professor

Chemistry
[College of Liberal Arts & Sciences]

Mentor

Lipid signaling, lipid binding proteins,

and eicosanoid biosynthesis in lungs

and other tissues

Yang Dai, PhD

Associate Professor

Bioengineering

[College of Engineering]

Mentor


Pharmacology

Mentor

Molecular pharmacology of platelet activation; platelet and endothelial cell interactions

Steven Dudek, MD
Dvision Chief, Pulmonary, Critical Care, Sleep and Allergy & Associate Professor

Medicine, Division of Pulmonary, Critical Care, Sleep and Allergy
(Pharmacology)

Mentor

Mechanistic characterization of vascular barrier function in models of inflammation

David Eddington, PhD
Associate Professor

Bioengineering
[College of Engineering]

Mentor

Microfluidics, oxygen modulation of cells and tissues, models of physiology and pathophysiology

Patricia Finn, MD
Chair, Department of Medicine & Earl M Bane Professor

Medicine, Division of Pulmonary, Critical Care, Sleep and Allergy
(Pharmacology)

Mentor

Pulmonary immunology in pathobiology

of vascular lung and asthma

Nissim Hay, PhD
Distinguished Professor

Biochemistry & Molecular Genetics

Mentor

Mechanisms of cell survival and cell cycle control; Akt regulation of cell function

Jeffrey Jacobson, MD
Associate Professor

Medicine, Division of Pulmonary, Critical Care, Sleep and Allergy
(Pharmacology)

Mentor

Lung endothelial cell barrier regulation and acute lung injury

Jack Kaplan, PhD
Benjamin Goldberg

Professor & Head

Biochemistry & Molecular Genetics
Center for Structural Biology

Mentor

Molecular studies of ATPases that

function as ion pumps

Andrei Karginov, PhD
Assistant Professor

Pharmacology
Cancer Center

Mentor

Regulation of endothelial cell function by phosphorylation-mediated signaling

Salman Khetani, PhD

Associate Professor

Bioengineering

[College of Engineering]

Mentor

Jan K. Kitajewski, PhD

Professor and Head

Physiology & Biophysics

Mentor

Angiogenesis in embryonic, adult, tumor, and reproductive states

Yulia Komarova, PhD
Associate Professor

Pharmacology

Mentor

Signaling mechanisms regulating endothelial barrier in lung

Biochemistry & Molecular Genetics

Mentor

Angiogenesis, cell growth, and differentiation

Medicine, Division of Pulmonary, Critical Care, Sleep and Allergy
(Pharmacology)
(Bioengineering)
[College of Engineering]

Mentor

Role of endothelial and macrophage ion channels in lung injury and inflammation;
endothelial biomechanics

James Lee, PhD

Associate Professor

Bioengineering

[College of Engineering]

Mentor

Bioengineering
[College of Engineering]

Mentor

Bioinformatics and systems

biology of proteins, RNA, networks,

and tissue patterning

Pharmacology
Center for Lung &

Vascular Biology

Mentor

Identification of signaling switches that compromise endothelial barrier function, and promotion of barrier repair in lungs

Bradley Merrill, PhD
Associate Professor

Biochemistry & Molecular Genetics

Mentor

Wnt/β-catenin signaling, Mesoderm/ endoderm lineage specification, specification of endothelial progenitors

Anesthesiology
Center for Lung &

Vascular Biology
(Pharmacology)

Mentor

Signaling mechanisms regulating paracellular and transcellular transport, vascular homeostasis, and

regeneration of airway epithelium

Viswanathan Natarajan, PhD

Earl M Bane Professor

Pharmacology
(Medicine, Division of Pulmonary, Critical Care, Sleep and Allergy)

Mentor

Role of reactive oxygen species and bioactive lipids in vascular endothelial signaling, injury and barrier integrity

Medicine, Division of Nephrology
(Surgery)

Mentor

Immunology, Systems Biology,

and lung transplantation

Biochemistry & Molecular Genetics

Mentor

Lung metastasis of breast and liver cancer

Pediatrics
(Pharmacology)

Mentor

Oxidative stress signaling and acute lung injury and repair in adults and neonates

Jalees Rehman, MD

Associate Professor

Medicine, Division of Cardiology

(Pharmacology)

Mentor

Biology of regenerative stem and progenitor cells in lung vascular system

Jae-Won Shin, PhD
Assistant Professor

Pharmacology & Bioengineering

Mentor

Stem cell mechanobiology and bioengineering for tissue regeneration by modulating blood and immune cells

Owen J. Tamplin, PhD Assistant Professor

Pharmacology (Bioengineering)

Mentor

Hematopoietic stem cell microenvironment; signals that regulate stem cell behavior

Chinnaswamy Tiruppathi, PhD

Associate Professor

Pharmacology
Center for Lung &

Vascular Biology

Mentor

Signaling pathways mediate in and resolve lung vascular inflammatory injury; ubiquitinediting enzyme A20 in lung injury

Biochemistry & Molecular Genetics

Mentor

Epithelial cell differentiation and

role in tissue injury

Kishore Wary, PhD
Associate Professor

Pharmacology
Center for Lung &

Vascular Biology (Bioengineering)
[College of Engineering]

Mentor

Lipid phosphate phosphatases in role of lung microvessel endothelial cells pro-apoptotic signaling

Medicine, Division of Pulmonary, Critical Care, Sleep and Allergy

Mentor

Lung Cancer and Wnt signaling